Novartis Thalassemia App Challenge

Submission Deadline

June 30, 2013

Contact

Graeme Ossey

Prizes

  • Five Finalists $5,000 each
  • First Place $100,000 + Demo Opportunity at Health 2.0's Fall 2013 Conference
  • Second Place $20,000
  • Third Place $5,000
First Place

Curatio

Curatio logo

Team Members

Lynda Brown-Ganzert and Alireza Davoodi

Curatio Thalassemia is helping Thalassemia patients get better, faster, together with real-time support from their families and treatment teams. Curatio Thalassemia builds on top of private social networks to give groups of patients the support they need to overcome their health and recovery issues.

Recent Updates

Congrats to the finalists! Thrive: Together in Thal, Jagriti Innovations, Circle of Support, Praxis Foundry, and Curatio!

Background

Thalassemia is a diverse family of genetic disorders affecting red blood cell production that cause anemia and consequently, patients suffer significant medical complications.1 Thalassemia can range from milder types to severe cases that start in infancy and require regular blood transfusions for patient survival2 and clinical complications can vary by type of thalassemia. Additionally, patients suffer from iron overload either as a consequence of the disease or because extra iron was absorbed during blood transfusions.3 Most patients with thalassemia are of South and Southeast Asian, Mediterranean or Middle Eastern origin, with immigration broadening the global prevalence.4

There is a need to develop an innovative app solution that increases Thalassemia patients’ (as well as their caretakers’) ability to manage the disease effectively including monitoring/tracking of key parameters, treatment/medication adherence and recording of daily personal facts, which help patients live active lives despite their condition.

The Challenge is open to any individual 18 years old or older as of their time of entry, and any organizational entity (corporation, non-profit, etc.) operating lawfully anywhere in any country or territory, except for Cuba, Iran, Sudan, Syria and North Korea. Employees of Sponsor, Administrator, each of their affiliates, and/or any other individual or entity associated with the development, judging, or administration of the Challenge as well as members of such persons' immediate families (spouses, children, siblings, parents), and persons living in the same household as such persons, whether or not related, are not eligible to participate in the Challenge. For more information on see Terms and Conditions.

Novartis Oncology has become a global leader in oncology and hematology through targeted research and open partnership in the pursuit of new therapies capable of transforming outcomes for people with cancer and other hematological diseases. We offer a wide range of innovative therapies to help physicians meet patient needs, with one of the broadest pipelines in the industry. Our research is driven by a distinctive scientific and clinical strategy, focusing on unmet medical needs and disease pathways.

References:

1. Weatherall DJ. The definition and epidemiology of non-transfusion-dependent thalassemia. Blood Reviews. 2012:26S:S3-S6
2. Taher AT, Musallam KM, Karimi M, El-Beshlawy A, Belhoul K, et al. Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study. Blood. 2010;115:1886-1892.
3. Musallam KM, Cappellini MD, Wood JC, Taher AT. Iron overload in non-transfusion-dependent thalassemia: a clinical perspective. Blood Reviews. 2012;26S:S16-19.
4. Thalassaemia International Federation. The Thalassaemia International Federation’s (TIF) New Focus: Addressing the Management of Non-Transfusion-Dependent Thalassaemias (NTDT). Position Paper 5.2. March 20, 2012. Accessed at: http://www.thalassaemia.org.cy/pdf/NTDT_Position_Paper_Final.pdf.
5. Taher AT, Cappellini MD, Musallam KM. Recent advances and treatment challenges in patients with non-transfusion-dependent thalassemia. Blood Reviews. 2012.26S:S1-2.

Description

Thalassemia patients face daily challenges in managing their disease. There is a critical need to develop an app solution, which minimizes the hassle of daily disease management. Novartis challenges the teams to develop an innovative smartphone/iPad application that increases Thalassemia patients’ (as well as the caretakers’) ability to manage the disease effectively (including monitoring/tracking of key parameters, treatment/medication adherence and recording of daily personal facts, which help patients live active lives despite their condition). Thalassemia patients live all around the world which means that teams need to consider multi-cultural differences in order to create an exceptional user experience. There are a number of disease management and adherence applications available in the market today, but many are just scratching the surface as to what is possible. As a result, we are looking for teams to be BOLD and INNOVATIVE in developing this solution. This includes building unique features and functionalities that:

  • Motivate, inspire and reinforce positive behaviors related to adherence in order to reach treatment goals
  • Enable patients to set and track goals - patients motivated by gaming features, receiving “awards”/incentives, receiving daily inspiration quotes and etc.
  • Provide users ability to share information and collaborate with others (most importantly with HCPs and also with caregiver, friends) via opt-in and password protection features
  • Educate, entertain and keep patient up to date on lifestyle and disease management topics

Successful solutions should also have such basic functions as the following:

  • Data-driven components that monitor patient’s progress over treatment term (see Addendum below)
  • Graphing of the collected parameter data
  • Easy to use, encourage repeat use, and avoid adding burden to patient’s daily routine
  • Treatment reminders and appointments
  • Global adaptability, including Non-English language options.
  • Capability to host educational videos, links to other relevant websites
  • Capability to connect to clinical publications and guidelines, medical education

Addendum: The following parameters are important to Thalassemia care (not all required for app)

Patient reported parameters:

  • Patient name
  • Patient Weight (date, value to monitor for growth over time)
  • Date of birth
  • Thalassemia Specific Medication Dosing schedule (iron chelation)
  • Other medications (name, dose, notes)
  • Allergies (description)
  • Other health conditions (name, notes)
  • Questions/notes from specific doctor visits
  • Side effects/illnesses experienced (date, notes)
  • Energy levels/Mood
  • Mobility
  • Diet/food

Parameters to be entered with physician support:

  • Diagnosis (date of diagnosis)
  • Transfusion history
  • History of pre-transfusion hemoglobin
  • Serum Ferritin (SF) level (date, value, monthly)
  • Liver Iron Concentration (LIC) (date, value, quarterly)
  • T2* - cardiac iron level
  • Hemoglobin level
  • X-ray extramedullary hematopoiesis
  • Serum creatinine (date, value, monthly)
  • Creatinine clearance (date, value, monthly)
  • Bilirubin
  • Alkaline phosphatase
  • Urine tests (date, notes - monthly)
  • Liver function (date, notes - monthly) – Serum transaminases (ALT, AST) + Gamma GT
  • Hearing/vision tests (date, notes - annually)
  • White blood cell counts (date, value, notes)
  • Thalassemia related complications (bolded – a certain type of thalassemia called Non-Transfusion-Dependent Thalassemia (“NTDT”)):
  • Splenectomy
  • Cholecystectomy
  • Gallstones
  • Cardiopathy
  • Abnormal liver enzymes
  • Liver disease
  • Hepatitis C and/or B infection
  • Hypogonadism
  • Diabetes mellitus
  • Hypothyroidism
  • Extramedullary haemopoiesis
  • Leg ulcers
  • Thrombotic events
  • Pulmonary hypertension (PHT)

Timeline

  • Registration Opens: May 20, 2013 at 9am ET
  • Phase I Deadline: June 30, 2013
  • Evaluation Period: July 1 – 12, 2013
  • Notification to Finalists: Week of July 15, 2013
  • Phase II Deadline: Sept. 8, 2013
  • Live, Virtual Judging: September 10, 2013
  • Announcement of Winner: Oct. 1, 2013

Review Panel

    • Global Thalassemia Experts
    • Thalassemia Patient Advocacy Group Leader
    • Novartis Oncology Internal Judging Members

Evaluation Criteria

Challenge will consist of 2 phases:

Phase I requires a mock-up or drawing of concept for the proposed application and a written proposal. Phase II will require the finalists to submit a full working application.Please see the submission criteria section for more submission details.

At the end of phase 1, the entries will be evaluated by a diverse review panel appointed by Novartis. At the end of phase 2, the 5 finalists will present their prototype applications to the judging panel. Three teams will be chosen by the judging panel to win prizes during this virtual, live judging session (see the timeline section for details).

Phase I:

  • Creativity, innovation and unique qualities of application (i.e. Game and/or gamification design characteristics that clearly drive engagement and experience)
  • Design, usability and intuitiveness of application
  • User appeal (simple and attractive interface) and potential for widespread adoption (global audience)
  • Capability for the app to be connected (via opt-in feature) to the tools (smartphones, tablets, PCs) used by others with whom the patient may want to share information (i.e. other patients, caregivers, HCPs)
  • Potential of partnership and future work with Novartis

Phase II:

  • All phase 1 criteria
  • Degree of development of application (prototype vs. polished product)

Submission Requirements

Phase I:

  1. Mock-up or drawing of concept
  2. 5-page or less written document explaining the proposed application, including information about:
    • Product features
    • Target users
    • Example use cases
    • Product development plan
    • Marketing plan
    • Submitting team profiles
    • Business model

Phase II:

  1. 5-7 slides describing the submitted application
  2. and a less than 5-minute video demonstrating the application
  3. Live demo and submission of app for testing

Terms & Conditions

NOVARTIS THALASSEMIA DISEASE MANAGEMENT APP CHALLENGE (the "Challenge")

OFFICIAL RULES
NO PURCHASE OR PAYMENT NECESSARY TO ENTER OR TO WIN. A PURCHASE WILL NOT IMPROVE YOUR CHANCES OF WINNING. VOID WHERE PROHIBITED.

SPONSOR: The sponsor of this Challenge is Novartis International Pharmaceuticals Corporation, One Health Plaza, East Hanover, NJ 07936-1080, USA ("Sponsor").

ADMINISTRATOR: The administrator of the Challenge is Health 2.0, LLC, 350 Townsend Street, #403, San Francisco, CA 94107 ("Administrator")

CHALLENGE DESCRIPTION: The Challenge submission period begins at 12:01 AM Eastern Time on Wednesday, May 22, 2013 and ends at 11:59 PM Eastern Time on Tuesday, October 1, 2013 ("Challenge Period"). The Challenge ends with the announcement of the competition winner on Monday, September 2013 at the Health 2.0 Fall Conference. Entry into the Challenge does not constitute entry into any other challenge or promotion, including, without limitation, other similar challenges or promotions offered by Sponsor and/or Administrator. By participating in the Challenge, each entrant unconditionally accepts and agrees to comply with and abide by these Official Rules and the decisions of Sponsor and/or Administrator, which shall be final and binding in all respects.

ELIGIBILITY: The Challenge is open to any individual 18 years old or older as of their time of entry, and any organizational entity (corporation, non-profit, etc.) operating lawfully anywhere in any country or territory, except for Cuba, Iran, Sudan, Syria and North Korea. Employees of Sponsor, Administrator, each of their affiliates, and/or any other individual or entity associated with the development, judging, or administration of the Challenge as well as members of such persons' immediate families (spouses, children, siblings, parents), and persons living in the same household as such persons, whether or not related, are not eligible to participate in the Challenge.

HOW TO ENTER: To enter go to the website located at www.health2challenge.org (the "Challenge Website"), complete the Official Entry Form, and enter your Submission demonstrating the Submission's capabilities and functionality as required by the instructions posted on the Challenge Website. You may enter either alone or as part of a team. Each Submission entered into the Challenge must meet the "Submission Requirements" described by the challenge Sponsor. Any Submission that, in Sponsor's sole discretion, does not meet the Submission Requirements will be disqualified.

Submissions must be received during the Challenge Period to be eligible. Administrator is the official timekeeper for the Challenge. No substitutions of new versions of Submissions will be accepted under any circumstances once the original Submission is submitted for consideration. In the event a dispute regarding the identity of the individual or team who actually submitted an entry cannot be resolved to Sponsor's and/or Administrator's satisfaction, the affected entry will be deemed ineligible. Except as otherwise stated in these Official Rules, personal information collected in connection with the Challenge will be used by Sponsor in accordance with Sponsor’s privacy policy available at [http://www.novartis.com/privacy-policy.shtml] and by Administrator in accordance with Administrator's privacy policy available on the Website and with any additional consent given by an entrant at the time of entry. All entry information and materials, including any copy of the Submission submitted to Sponsor, become the property of Sponsor and will not be acknowledged or returned. Proof of submission is not considered proof of delivery to or receipt of such entry. Furthermore, Sponsor and Administrator shall have no liability for any Submission that is lost, intercepted, or not received by Sponsor and/or Administrator. Sponsor and Administrator assume no liability or responsibility for any error, omission, interruption, deletion, theft, or destruction or unauthorized access to, or alteration of, Submissions.

REPRESENTATIONS AND WARRANTIES/INDEMNIFICATION: By participating in the Challenge, each entrant represents, warrants, and covenants as follows: (a) entrant is the sole author, creator, and owner of the Submission; (b) the Submission is not the subject of any actual or threatened litigation or claim; (c) the Submission does not and will not violate or infringe upon the intellectual property rights, privacy rights, publicity rights, or other legal rights of any third party; (d) the Submission does not and will not contain any harmful computer code (sometimes referred to as "malware," "viruses" or "worms"); and (e) the Submission, and entrants’ use of the Submission, does not and will not violate any applicable laws or regulations, including, without limitation, applicable export control laws and regulations of the U.S. and other jurisdictions. If the Submission includes any third party works (such as third party content or open source code), entrant must be able to provide, upon Sponsor and/or Administrator's request, all appropriate licenses and releases for such third party works. In the event entrant cannot provide all required licenses and releases, Sponsor reserves the right, in Sponsor's sole discretion, to disqualify the applicable Submission, or seek to secure the licenses and releases for Sponsor's benefit and allow the applicable Submission to remain in the Challenge. Entrants will indemnify, defend, and hold harmless Sponsor and Administrator from and against all third party claims, actions, or proceedings of any kind and from any and all damages, liabilities, costs, and expenses relating to or arising from entrant's Submission or any breach or alleged breach of any of the representations, warranties, and covenants of entrant hereunder. Sponsor and/or Administrator reserve the right to disqualify any Submission that Sponsor and/or Administrator, in its sole discretion, deems not to comply with these Official Rules.

SUBMISSION LICENSE: EACH ENTRANT RETAINS TITLE AND FULL OWNERSHIP IN AND TO THEIR SUBMISSION. ENTRANT EXPRESSLY RESERVES ALL INTELLECTUAL PROPERTY RIGHTS NOT EXPRESSLY GRANTED UNDER THIS AGREEMENT. By participating in the Challenge, each entrant hereby irrevocably grants to Sponsor and Administrator a limited, non-exclusive, royalty free, worldwide, license and right to use the Submission to the extent necessary to administer the Challenge, and to publically perform and publically display the Submission, including, without limitation, for advertising and promotional purposes relating to the Challenge.

PUBLICITY RELEASE: By participating in the Challenge, in addition to any other grants granted herein or which may be granted in any other agreement entered into between Sponsor and/or Administrator, on the one hand, and any entrant in the Challenge, on the other hand, each entrant hereby irrevocably (a) grants to Sponsor and Administrator the right to use such entrant's name, likeness, image, and biographical information in any and all media for any purpose, including, without limitation, advertising and promotional purposes relating to the Challenge and (b) releases Sponsor and Administrator from any liability with respect thereto.

WINNER SELECTION/EVALUATION CRITERIA: Sponsor, in its sole discretion and with input from a review panel appointed by Sponsor, will select 5 winners in phase 1 and 3 winners in phase 2 among all eligible entries based on the following evaluation criteria:

  • Innovation and unique qualities of application

  • Usability and design of application
  • User appeal and potential for widespread adoption (global audience)
  • Degree of development of application (prototype vs. polished product)
  • Potential of partnership and future work with Novartis

The evaluation criteria are to be applied and the winners selected in the sole discretion of Sponsor, with input from the review panel. By participating in the Challenge, each entrant into the Challenge acknowledges and agrees that such evaluations may differ from person to person and agrees to be bound by and not challenge the final decisions of Sponsor.

NOTICE TO WINNERS: Attempts to notify potential winners will be made using the contact information provided on the winner's Official Entry Form. Sponsor and Administrator are not responsible for e-mail or other communication problems of any kind. If, despite reasonable efforts, a potential winner does not respond within five (5) days of the first notification attempt (or a shorter time if deemed necessary by Sponsor), or if the prize or prize notification is returned as unclaimed or undeliverable to such potential winner, such potential winner will forfeit his or her prize. If any potential prize winner forfeits a prize or is found to be ineligible, or if he or she has not complied with these Official Rules or declines the applicable prize for any reason prior to award, such potential prize winner will be disqualified and the Sponsor in its sole discretion will determine whether to select an alternate winner or not to award the prize. ANTICIPATED NUMBER OF ENTRANTS: It is anticipated that many individuals or teams will enter this Challenge. 5 submissions will be selected as winners in phase 1 and 3 submissions will be selected as winners in phase 2. Actual odds of winning depend on the number of eligible entries received. Sponsor and Administrator cannot accurately predict the number of entrants who will participate in the Challenge. In the event that Sponsor, in its sole discretion, deems that an insufficient number of eligible entries are received, or that Sponsor and/or Administrator is prevented from awarding the prize or continuing with the Challenge as contemplated herein by any event beyond its control, including, without limitation, fire, flood, natural or man-made epidemic, earthquake, explosion, labor dispute or strike, act of God or public enemy, satellite or equipment failure, riot or civil disturbance, terrorist threat or activity, war (declared or undeclared) or any federal state or local government law, order, or regulation, public health crisis, order of any court or jurisdiction, or other cause not reasonably within Sponsor's control ("Force Majeure"), Sponsor and/or Administrator shall have the right to modify, suspend, or terminate the Challenge.

PRIZES:
There will be a tiered award structure:

  • Phase 1

    • 5 prizes - $5,000 each ($25,000 total)
  • Phase 2
    • First Prize - $100,000 + demo opportunity at Health 2.0’s Fall 2013 conference
    • Second Prize - $20,000
    • Third Prize - $5,000

GENERAL PRIZE CONDITIONS: The potential winner may be required to execute an Affidavit of Eligibility, a Liability Release and (where imposing such condition is legal) a Publicity Release (collectively "Prize Claim Documents”). If a winner fails or refuses to sign and return all Prize Claim Documents within five (5) days of Sponsor's and/or Administrator's request (or a shorter time if deemed necessary by Sponsor), the winner may be disqualified and an alternate winner may be selected. No more than the advertised number of prizes will be awarded. No cash alternative or substitution or transfer of prizes will be allowed, except Sponsor reserves the right in its sole discretion to substitute prizes of comparable value, in whole or in part, for any reason. THE WINNER IS RESPONSIBLE FOR REPORTING AND PAYING ANY INCOME TAXES OR OTHER TAXES THAT MAY APPLY TO ACCEPTING A PRIZE; SPONSOR AND ADMINISTRATOR ARE NOT RESPONSIBLE FOR AND WILL NOT PAY ANY SUCH TAXES.

DATES/DEADLINES: Because of the unique nature and scope of the Challenge, Sponsor and Administrator reserve the right, in addition to those other rights reserved herein, to modify any dates or deadlines set forth in these Official Rules or otherwise governing the Challenge.

GENERAL LIABILITY RELEASE/FORCE MAJEURE: Each entrant agrees that neither Sponsor nor Administrator (a) shall be responsible or liable for any losses, damages, or injuries of any kind (including death) resulting from participation in the Challenge or any Challenge-related activity, or from entrants' acceptance, receipt, possession, use, or misuse of any prize, and (b) has made any warranty, representation, or guarantee, express or implied, in fact or in law, with respect to any prize, including, without limitation, regarding such prize's merchantability or fitness for a particular purpose. Entrants will indemnify, defend, and hold harmless Sponsor and Administrator from and against all third party claims, actions, or proceedings of any kind and from any and all damages, liabilities, costs, and expenses relating to or arising from entrant's participation in the Challenge. Neither Sponsor nor Administrator assume responsibility for any damage to an entrant's computer system which is occasioned by accessing the Website or other Challenge-related websites or participating in the Challenge, or for any computer system, phone line, hardware, software, or program malfunctions, or other errors, failures, delayed computer transmissions, or network connections that are human or technical in nature. Without limiting the generality of the foregoing, neither Sponsor nor Administrator are responsible for incomplete, illegible, misdirected, misprinted, late, lost, postage-due, damaged, or stolen entries or prize notifications; or for lost, interrupted, inaccessible, or unavailable networks, servers, satellites, Internet Service Providers, websites, or other connections; or for miscommunications, failed, jumbled, scrambled, delayed, or misdirected computer, telephone, cable transmissions or other communications; or for any technical malfunctions, failures, difficulties, or other errors of any kind or nature; or for the incorrect or inaccurate capture of information, or the failure to capture any information. Sponsor and Administrator each reserve the right in their sole discretion to disqualify any individual who is found to be tampering with the entry process or the operation of the Challenge or Website or other Challenge-related websites, to be acting in violation of these Official Rules, or to be acting in an unsportsmanlike or disruptive manner, or with the intent to disrupt or undermine the legitimate operation of the Challenge, or to annoy, abuse, threaten, or harass any other person, and Sponsor and Administrator each reserve the right to seek damages and other remedies from any such person to the fullest extent permitted by law. If the Challenge is terminated for Force Majeure before expiration of the Challenge Period, Sponsor may in its sole discretion, but is not required to, select a winner from all eligible, non-suspect entries received as of the date of the event giving rise to the termination. These Official Rules cannot be modified or amended in any way except in a written document issued in accordance with the law by a duly authorized representative of both Sponsor and Administrator. The invalidity or unenforceability of any provision of these Official Rules shall not affect the validity or enforceability of any other provision. In the event that any provision is determined to be invalid or otherwise unenforceable or illegal, these Official Rules shall otherwise remain in effect and shall be construed in accordance with their terms as if the invalid or illegal provision were not contained herein.
GOVERNING LAW/JURISDICTION: ALL ISSUES AND QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, INTERPRETATION, AND ENFORCEABILITY OF THESE OFFICIAL RULES OR THE RIGHTS AND OBLIGATIONS OF ENTRANTS, SPONSOR AND/OR ADMINISTRATOR IN CONNECTION WITH THE CHALLENGE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF CALIFORNIA WITHOUT GIVING EFFECT TO ANY CHOICE OF LAW OR CONFLICT OF LAWS RULES OR PROVISIONS. ANY LEGAL CLAIMS ARISING FROM OR RELATING TO THE CHALLENGE OR THESE OFFICIAL RULES MUST BE BROUGHT IN THE FEDERAL OR STATE COURTS LOCATED IN SAN FRANCISCO, CALIFORNIA.
WINNERS LIST/OFFICIAL RULES: To obtain any legally-required winners list (after the conclusion of the Challenge) or a copy of these Official Rules, send a self-addressed envelope with the proper postage affixed to: Health 2.0, LLC, Attn: Health 2.0 Developer Challenge, 350 Townsend Street, #403, San Francisco, CA 94107. Please specify "winners list" or "Official Rules" and the name of the specific Challenge in your request.
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